| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| amiB | hflC | STM4358 | STM4364 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | 0.754 |
| amiB | hflK | STM4358 | STM4363 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | 0.704 |
| amiB | hflX | STM4358 | STM4362 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Putative GTP-ase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.761 |
| amiB | hfq | STM4358 | STM4361 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Host factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells. | 0.758 |
| amiB | miaA | STM4358 | STM4360 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.963 |
| amiB | yjeE | STM4358 | STM4357 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Putative nucleotide-binding protein; Similar to E. coli orf, hypothetical protein (AAC77125.1); Blastp hit to AAC77125.1 (153 aa), 93% identity in aa 1 - 152. | 0.943 |
| amiB | yjeF | STM4358 | STM4356 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...] | 0.955 |
| amiB | yjeT | STM4358 | STM4365 | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77133.1); Blastp hit to AAC77133.1 (65 aa), 89% identity in aa 1 - 65. | 0.630 |
| hflB | hflC | STM3296 | STM4364 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | 0.996 |
| hflB | hflK | STM3296 | STM4363 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | 0.996 |
| hflB | hflX | STM3296 | STM4362 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Putative GTP-ase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.609 |
| hflB | hfq | STM3296 | STM4361 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Host factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells. | 0.587 |
| hflB | miaA | STM3296 | STM4360 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.608 |
| hflB | ycfC | STM3296 | STM1233 | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | Unknown membrane associated protein; Similar to E. coli orf, hypothetical protein (AAC74216.1); Blastp hit to AAC74216.1 (213 aa), 94% identity in aa 1 - 213. | 0.452 |
| hflC | amiB | STM4364 | STM4358 | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | N-acetylmuramoyl-l-alanine amidase II; Cell-wall hydrolase involved in septum cleavage during cell division. | 0.754 |
| hflC | hflB | STM4364 | STM3296 | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | ATP-dependent zinc-metallo protease; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; In the central section; belongs to the AAA ATPase family. | 0.996 |
| hflC | hflK | STM4364 | STM4363 | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could encode or regulate a protease. | 0.999 |
| hflC | hflX | STM4364 | STM4362 | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | Putative GTP-ase; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.946 |
| hflC | hfq | STM4364 | STM4361 | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | Host factor I for bacteriophage Q beta replication; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity). Plays a central regulatory role in the microbial response to space flight conditions. Is essential for virulence and is required for efficient invasion of non-phagocytic cells. | 0.886 |
| hflC | miaA | STM4364 | STM4360 | Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.941 |