Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
yjeTPutative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77133.1); Blastp hit to AAC77133.1 (65 aa), 89% identity in aa 1 - 65. (65 aa)    
Predicted Functional Partners:
yjeF
Putative sugar kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both ep [...]
     
 0.861
hflC
Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could regulate a protease.
     
 0.776
yifL
Putative outer membrane lipoprotein.
      
 0.769
hflK
Component of modulator for protease specific for FtsH phage lambda cII repressor; HflC and HflK could encode or regulate a protease.
     
 0.764
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
     
 0.752
ydiL
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC74759.1); Blastp hit to AAC74759.1 (127 aa), 59% identity in aa 10 - 127.
      
 0.727
yjeE
Putative nucleotide-binding protein; Similar to E. coli orf, hypothetical protein (AAC77125.1); Blastp hit to AAC77125.1 (153 aa), 93% identity in aa 1 - 152.
     
 0.717
stcB
Similar to E. coli putative chaperone (AAC75171.1); Blastp hit to AAC75171.1 (239 aa), 64% identity in aa 16 - 239.
      
 0.714
ydiK
Putative permease; Similar to E. coli orf, hypothetical protein (AAC74758.1); Blastp hit to AAC74758.1 (370 aa), 89% identity in aa 1 - 370.
      
 0.706
ytfP
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77179.1); Blastp hit to AAC77179.1 (113 aa), 92% identity in aa 1 - 113.
      
 0.680
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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