Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ytfFPutative cationic amino acid transporter; Similar to E. coli putative transmembrane subunit (AAC77167.1); Blastp hit to AAC77167.1 (324 aa), 81% identity in aa 4 - 323. (321 aa)    
Predicted Functional Partners:
yeaS
Putative transport protein; Exporter of leucine; Belongs to the Rht family.
      
 0.897
cysQ
CysQ protein; Converts adenosine-3',5'-bisphosphate (PAP) to AMP.
      
 0.896
yddG
Putative permease; Similar to E. coli orf, hypothetical protein (AAD13437.1); Blastp hit to AAD13437.1 (293 aa), 85% identity in aa 20 - 292.
      
 0.860
cpdB
2',3'-cyclic-nucleotide 2'-phosphodiesterase; This bifunctional enzyme catalyzes two consecutive reactions during ribonucleic acid degradation. Converts a 2',3'-cyclic nucleotide to a 3'-nucleotide and then the 3'-nucleotide to the corresponding nucleoside and phosphate; Belongs to the 5'-nucleotidase family.
   
  
 0.859
mglB
Galactose transport protein; This protein is involved in the active transport of galactose and glucose. It plays a role in the chemotaxis towards the two sugars by interacting with the trg chemoreceptor.
      
 0.676
ytfE
Putative cell morphogenesis; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.
  
    0.613
ytfG
Similar to E. coli putative oxidoreductase (AAC77168.1); Blastp hit to AAC77168.1 (286 aa), 80% identity in aa 1 - 278.
  
    0.588
astA
Arginine succinyltransferase; Catalyzes the transfer of succinyl-CoA to arginine to produce N(2)-succinylarginine.
      
 0.579
ypfG
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC75519.1); Blastp hit to AAC75519.1 (347 aa), 77% identity in aa 1 - 347.
  
    0.570
ybhN
Putative negative regulator; Similar to E. coli orf, hypothetical protein (AAC73875.1); Blastp hit to AAC73875.1 (318 aa), 89% identity in aa 1 - 318.
  
    0.482
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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