STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
STM4419Sugar (and other) transporter; Similar to E. coli xylose-proton symport (AAC77001.1); Blastp hit to AAC77001.1 (491 aa), 33% identity in aa 58 - 486, 39% identity in aa 3 - 106; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (478 aa)    
Predicted Functional Partners:
STM4420
Putative inner membrane protein.
   
  
 0.997
STM4423
Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 27% identity in aa 38 - 283.
   
  
 0.993
iolG
Putative dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose).
  
 0.986
iolE
Putative endonuclease; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family.
  
  
 0.984
STM4427
Putative endonuclease.
   
    0.978
srfJ
Activated by transcription factor SsrB; Similar to Homo sapiens lysosomal glucosyl ceramidase; SrfJ (gi|8347262); Belongs to the glycosyl hydrolase 30 family.
  
  
 0.962
STM4434
Similar to E. coli putative transport protein (AAC77235.1); Blastp hit to AAC77235.1 (425 aa), 22% identity in aa 167 - 417, 21% identity in aa 40 - 145.
  
    0.959
STM4418
Sugar (and other) transporter; Similar to E. coli xylose-proton symport (AAC77001.1); Blastp hit to AAC77001.1 (491 aa), 41% identity in aa 58 - 487, 47% identity in aa 5 - 103; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
  
0.957
STM4421
Similar to E. coli phenylacetaldehyde dehydrogenase (AAC74467.1); Blastp hit to AAC74467.1 (500 aa), 34% identity in aa 22 - 500.
   
    0.931
STM4428
Similar to E. coli putative transport protein (AAC75382.1); Blastp hit to AAC75382.1 (392 aa), 48% identity in aa 9 - 391.
   
    0.931
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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