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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
iolGPutative dehydrogenase; Involved in the oxidation of myo-inositol (MI) to 2-keto-myo- inositol (2KMI or 2-inosose). (336 aa)    
Predicted Functional Partners:
iolE
Putative endonuclease; Catalyzes the dehydration of inosose (2-keto-myo-inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D-(3,5/4)- trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi-inositol). Belongs to the IolE/MocC family.
 
 
 0.999
STM4420
Putative inner membrane protein.
 
  
 0.997
STM4427
Putative endonuclease.
 
 
 0.997
STM4419
Sugar (and other) transporter; Similar to E. coli xylose-proton symport (AAC77001.1); Blastp hit to AAC77001.1 (491 aa), 33% identity in aa 58 - 486, 39% identity in aa 3 - 106; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.
  
 0.986
STM4435
Putative cytoplasmic protein.
 
  0.982
STM4423
Similar to E. coli putative ARAC-type regulatory protein (AAC74766.1); Blastp hit to AAC74766.1 (303 aa), 27% identity in aa 38 - 283.
  
  
 0.976
STM4433
Putative thiamine pyrophosphate-requiring enzyme; Oxidoreductase family; similar to E. coli putative virulence factor (AAC74152.1); Blastp hit to AAC74152.1 (307 aa), 29% identity in aa 1 - 188, 52% identity in aa 272 - 296.
  
 
 
0.955
STM4436
Putative endonuclease.
 
  
 0.951
STM4431
Putative thiamine pyrophosphate-requiring enzyme; Similar to E. coli acetolactate synthase I, valine-sensitive, large subunit (AAC76694.1); Blastp hit to AAC76694.1 (562 aa), 27% identity in aa 26 - 326, 34% identity in aa 12 - 126; Belongs to the TPP enzyme family.
 
  
 0.939
STM4432
Putative thiamine pyrophosphate-requiring enzyme; Similar to E. coli glyoxylate carboligase (AAC73609.1); Blastp hit to AAC73609.1 (593 aa), 33% identity in aa 421 - 539.
 
  
 0.924
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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