Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
STM4448Putative phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type). (637 aa)    
Predicted Functional Partners:
mtlA
Similar to E. coli PTS system, mannitol-specific enzyme IIABC components (AAC76623.1); Blastp hit to AAC76623.1 (637 aa), 95% identity in aa 1 - 637.
 
  
 0.987
STM4447
Putative periplasmic protein.
 
    0.918
STM4445
Putative dihydroorotase.
 
     0.911
STM4446
Putative selenocysteine synthase; [L-seryl-tRNA(Ser) selenium transferase].
 
    0.905
STM2344
Similar to E. coli putative PTS system enzyme II A component (AAC77152.1); Blastp hit to AAC77152.1 (154 aa), 41% identity in aa 12 - 149.
  
 0.902
STM4444
Putative inner membrane protein.
 
    0.861
STM4443
Putative inner membrane protein.
 
     0.858
ptsA
General PTS family enzyme I; Similar to E. coli PEP-protein phosphotransferase system enzyme I (AAC76929.1); Blastp hit to AAC76929.1 (711 aa), 90% identity in aa 1 - 711.
  
 
 0.857
STM4441
Putative cytoplasmic protein.
 
     0.852
ptxA
Putative PTS enzyme IIsga subunit; The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. The enzyme II UlaABC PTS system is involved in ascorbate transport.
  
 0.839
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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