Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
idnTGntP family L-idonate transport protein; Similar to E. coli L-idonate transporter (AAC77222.1); Blastp hit to AAC77222.1 (439 aa), 94% identity in aa 1 - 439. (439 aa)    
Predicted Functional Partners:
idnR
L-idonate regulator; GalR/LacI family; similar to E. coli L-idonate transcriptional regulator (AAC77221.1); Blastp hit to AAC77221.1 (332 aa), 89% identity in aa 1 - 332.
  
  
 0.944
idnO
5-keto-D-gluconate-5-reductase; Similar to E. coli 5-keto-D-gluconate 5-reductase (AAC77223.1); Blastp hit to AAC77223.1 (254 aa), 92% identity in aa 1 - 254; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.915
hcaT
Similar to E. coli MFS (major facilitator superfamily) transporter (AAC75589.1); Blastp hit to AAC75589.1 (379 aa), 88% identity in aa 1 - 376.
   
  
 0.897
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
      
 0.855
idnD
Similar to E. coli L-idonate dehydrogenase (AAC77224.1); Blastp hit to AAC77224.1 (343 aa), 82% identity in aa 1 - 343.
  
  
 0.816
idnK
Similar to E. coli gluconate kinase, thermosensitive glucokinase (AAC77225.1); Blastp hit to AAC77225.1 (187 aa), 86% identity in aa 1 - 171.
 
  
 0.691
rihC
Putative purine nucleoside hydrolase; Hydrolyzes both purine and pyrimidine ribonucleosides with a broad-substrate specificity.
   
  
 0.657
yjgQ
Putative permease; Similar to E. coli orf, hypothetical protein (AAC77219.1); Blastp hit to AAC77219.1 (361 aa), 97% identity in aa 2 - 361.
      
 0.541
gntK
Thermoresistant; similar to E. coli gluconokinase 2, thermoresistant (AAC76462.1); Blastp hit to AAC76462.1 (162 aa), 96% identity in aa 1 - 161.
 
  
 0.486
yohC
Putative transport protein; Similar to E. coli orf, hypothetical protein (AAC75196.1); Blastp hit to AAC75196.1 (203 aa), 91% identity in aa 9 - 203.
   
  
 0.460
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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