| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| STM1128 | acs | STM1128 | STM4275 | Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.439 |
| STM1128 | prpE | STM1128 | STM0371 | Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | 0.439 |
| STM1128 | yjiY | STM1128 | STM4532 | Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.534 |
| acs | STM1128 | STM4275 | STM1128 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.439 |
| acs | prpE | STM4275 | STM0371 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | 0.923 |
| acs | putP | STM4275 | STM1125 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.484 |
| acs | yjiY | STM4275 | STM4532 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.518 |
| prpE | STM1128 | STM0371 | STM1128 | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | Similar to E. coli putative cotransporter (AAC76702.1); Blastp hit to AAC76702.1 (571 aa), 22% identity in aa 7 - 478; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.439 |
| prpE | acs | STM0371 | STM4275 | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.923 |
| prpE | putP | STM0371 | STM1125 | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | 0.497 |
| prpE | yjiY | STM0371 | STM4532 | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.511 |
| putP | acs | STM1125 | STM4275 | SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.484 |
| putP | prpE | STM1125 | STM0371 | SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Putative acetyl-CoA synthetase, propionate catabolism operon; Catalyzes the synthesis of propionyl-CoA from propionate and CoA. Also converts acetate to acetyl-CoA but with a lower specific activity. | 0.497 |
| putP | yjiY | STM1125 | STM4532 | SSS family major sodium/proline symporter; Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.622 |
| sbmA | yehT | STM0376 | STM2158 | Putative ABC superfamily transporter; Similar to E. coli sensitivity to microcin B17, possibly envelop protein (AAC73480.1); Blastp hit to AAC73480.1 (406 aa), 92% identity in aa 1 - 406. | Putative regulator; Member of the two-component regulatory system BtsS/BtsR. BtsR regulates expression of btsT by binding to its promoter region. | 0.579 |
| sbmA | yjiY | STM0376 | STM4532 | Putative ABC superfamily transporter; Similar to E. coli sensitivity to microcin B17, possibly envelop protein (AAC73480.1); Blastp hit to AAC73480.1 (406 aa), 92% identity in aa 1 - 406. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.716 |
| ybdD | yjiA | STM0601 | STM4530 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77309.1); Blastp hit to AAC77309.1 (67 aa), 73% identity in aa 1 - 67. | Putative cobalamin synthesis protein; Similar to E. coli orf, hypothetical protein (AAC77308.1); Blastp hit to AAC77308.1 (284 aa), 90% identity in aa 1 - 284. | 0.692 |
| ybdD | yjiY | STM0601 | STM4532 | Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77309.1); Blastp hit to AAC77309.1 (67 aa), 73% identity in aa 1 - 67. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.894 |
| ybjE | yjiY | STM0938 | STM4532 | Similar to E. coli putative surface protein (AAC73961.1); Blastp hit to AAC73961.1 (315 aa), 88% identity in aa 17 - 315. | Similar to E. coli putative carbon starvation protein (AAC77310.1); Blastp hit to AAC77310.1 (721 aa), 96% identity in aa 6 - 721. | 0.577 |
| yehT | sbmA | STM2158 | STM0376 | Putative regulator; Member of the two-component regulatory system BtsS/BtsR. BtsR regulates expression of btsT by binding to its promoter region. | Putative ABC superfamily transporter; Similar to E. coli sensitivity to microcin B17, possibly envelop protein (AAC73480.1); Blastp hit to AAC73480.1 (406 aa), 92% identity in aa 1 - 406. | 0.579 |