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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dnaTPrimosomal protein I; This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'. (179 aa)    
Predicted Functional Partners:
dnaC
Chromosome replication protein; Initiation and chain elongation; similar to E. coli chromosome replication; initiation and chain elongation (AAC77317.1); Blastp hit to AAC77317.1 (245 aa), 93% identity in aa 1 - 245.
  
  
 0.988
priB
Primosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS). During primosome assembly it facilitates the complex formation between PriA and DnaT; Belongs to the PriB family.
    
 0.987
priC
Similar to E. coli primosomal replication protein N'' (AAC73569.1); Blastp hit to AAC73569.1 (175 aa), 73% identity in aa 5 - 175.
      
 0.973
dnaB
Putative replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins.
   
 0.961
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
    
 0.891
holD
DNA polymerase III, psi subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is unknown.
   
  
 0.776
yjjA
Similar to E. coli putative glycoprotein/receptor (AAC77316.1); Blastp hit to AAC77316.1 (165 aa), 68% identity in aa 3 - 165.
       0.631
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 3'-5' and 5'-3' exonuclease activity. It is able to utilize nicked circular duplex DNA as a template and can unwind the parental DNA strand from its template.
      
 0.579
yjjB
Putative inner membrane protein; Similar to E. coli orf, hypothetical protein (AAC77319.1); Blastp hit to AAC77319.1 (108 aa), 89% identity in aa 1 - 108.
     
 0.555
yjjP
Similar to E. coli putative structural protein (AAC77320.1); Blastp hit to AAC77320.1 (277 aa), 90% identity in aa 19 - 277.
       0.553
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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