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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yjjWPyruvate formate lyase activating enzyme; Similar to E. coli putative activating enzyme (AAC77332.1); Blastp hit to AAC77332.1 (287 aa), 81% identity in aa 1 - 287. (287 aa)    
Predicted Functional Partners:
yjjI
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77333.1); Blastp hit to AAC77333.1 (516 aa), 89% identity in aa 1 - 516.
  
 0.998
pflB
Pyruvate formate lyase I, induced anaerobically; Similar to E. coli formate acetyltransferase 1 (AAC73989.1); Blastp hit to AAC73989.1 (760 aa), 96% identity in aa 1 - 760.
 
  
 0.902
pflF
Similar to E. coli putative formate acetyltransferase (AAC73910.1); Blastp hit to AAC73910.1 (810 aa), 95% identity in aa 1 - 810.
  
 0.873
pflD
Putative pyruvate formate lyase II; Similar to E. coli formate acetyltransferase 2 (AAC76933.1); Blastp hit to AAC76933.1 (765 aa), 92% identity in aa 1 - 765.
  
 0.873
tdcE
Pyruvate formate-lyase 4; Similar to E. coli probable formate acetyltransferase 3 (AAC76149.1); Blastp hit to AAC76149.1 (746 aa), 93% identity in aa 1 - 741; 2-ketobutyrate formate-lyase.
 
  
 0.868
yfiD
Putative formate acetyltransferase; Acts as a radical domain for damaged PFL and possibly other radical proteins.
  
   
 0.848
hydN
Similar to E. coli involved in electron transport from formate to hydrogen, Fe-S centers (AAC75755.1); Blastp hit to AAC75755.1 (175 aa), 95% identity in aa 1 - 173.
      
 0.696
adhE
Similar to E. coli CoA-linked acetaldehyde dehydrogenase and iron-dependent alcohol dehydrogenase; pyruvate-formate-lyase deactivase (AAC74323.1); Blastp hit to AAC74323.1 (891 aa), 97% identity in aa 1 - 891; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
 
  
 0.634
deoC
2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
       0.571
nrdD
Anaerobic ribonucleoside-triphosphate reductase; Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. Belongs to the anaerobic ribonucleoside-triphosphate reductase family.
 
  
 0.562
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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