Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
yjjIPutative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77333.1); Blastp hit to AAC77333.1 (516 aa), 89% identity in aa 1 - 516. (516 aa)    
Predicted Functional Partners:
yjjW
Pyruvate formate lyase activating enzyme; Similar to E. coli putative activating enzyme (AAC77332.1); Blastp hit to AAC77332.1 (287 aa), 81% identity in aa 1 - 287.
  
 0.990
ycdC
Putative transcriptional repressor (TetR/AcrR family); Similar to E. coli putative tet operon regulator (AAC74098.1); Blastp hit to AAC74098.1 (212 aa), 83% identity in aa 1 - 212.
      
 0.859
dpiB
Sensory histidine kinase in two-component regulatory system with DpiA; Regulation of cit operon and plasmid inheritance genes; similar to E. coli putative sensor-type protein (AAC73720.1); Blastp hit to AAC73720.1 (552 aa), 86% identity in aa 2 - 552.
      
 0.856
dmsA
Similar to E. coli anaerobic dimethyl sulfoxide reductase subunit A (AAC73980.1); Blastp hit to AAC73980.1 (785 aa), 93% identity in aa 1 - 784; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
   
    0.719
ttk
Putative TetR/ArcR family transcriptional regulator; Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions.
      
 0.718
yhbU
Similar to E. coli putative collagenase (AAC76192.1); Blastp hit to AAC76192.1 (331 aa), 96% identity in aa 1 - 331.
  
    0.672
ygcF
Putative organic radical activating enzymes; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.
  
 
 0.657
nrdG
Anaerobic ribonucleotide reductase activating protein; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
  
 
 0.657
deoC
2-deoxyribose-5-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate.
  
    0.561
narG
Similar to E. coli nitrate reductase 1, alpha subunit (AAC74308.1); Blastp hit to AAC74308.1 (1247 aa), 95% identity in aa 1 - 1247; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.547
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
Server load: medium (50%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.