Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gpmBSimilar to E. coli phosphoglyceromutase 2 (AAC77348.1); Blastp hit to AAC77348.1 (215 aa), 91% identity in aa 1 - 215; Belongs to the phosphoglycerate mutase family. GpmB subfamily. (215 aa)    
Predicted Functional Partners:
pmgI
Phosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
     
 0.949
gpmA
Phosphoglyceromutase 1; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
 
 0.946
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
     
 0.933
pgk
Similar to E. coli phosphoglycerate kinase (AAC75963.1); Blastp hit to AAC75963.1 (387 aa), 97% identity in aa 1 - 387.
     
 0.912
serA
Similar to E. coli D-3-phosphoglycerate dehydrogenase (AAC75950.1); Blastp hit to AAC75950.1 (410 aa), 96% identity in aa 1 - 410; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
 0.908
glxK
Glycerate kinase II; Similar to E. coli orf, hypothetical protein (AAC73616.1); Blastp hit to AAC73616.1 (381 aa), 80% identity in aa 1 - 379; Belongs to the glycerate kinase type-1 family.
     
 0.900
STM2959
Putative glycerate kinase 2; Similar to E. coli orf, hypothetical protein (AAC76158.1); Blastp hit to AAC76158.1 (408 aa), 68% identity in aa 28 - 405; Belongs to the glycerate kinase type-1 family.
     
 0.900
garK
Glycerate kinase; Similar to E. coli orf, hypothetical protein (AAC76158.1); Blastp hit to AAC76158.1 (408 aa), 86% identity in aa 28 - 408; Belongs to the glycerate kinase type-1 family.
     
 0.900
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
    
 0.875
tktB
Transketolase 2 isozyme; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
    
 0.864
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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