STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
creDSimilar to E. coli tolerance to colicin E2 (AAC77353.1); Blastp hit to AAC77353.1 (450 aa), 73% identity in aa 1 - 450. (449 aa)    
Predicted Functional Partners:
creC
Sensory kinase (alternative) in two-component regulatory system with CreB (or alternatively PhoB); Senses catabolite repression; similar to E. coli catabolite repression sensor kinase for PhoB; alternative sensor for pho regulon (AAC77352.1); Blastp hit to AAC77352.1 (474 aa), 80% identity in aa 1 - 474.
 
  
 0.963
creB
Response regulator in two-component regulatory system with CreC; OmpR family; similar to E. coli catabolic regulation response regulator (AAC77351.1); Blastp hit to AAC77351.1 (229 aa), 83% identity in aa 1 - 229.
 
   
 0.829
creA
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC77350.1); Blastp hit to AAC77350.1 (157 aa), 89% identity in aa 1 - 157.
     
 0.673
pbpC
Transglycosylase of penicillin-binding protein 1c; Similar to E. coli putative peptidoglycan enzyme (AAC75572.1); Blastp hit to AAC75572.1 (770 aa), 82% identity in aa 7 - 767.
  
     0.628
STM2532
Putative inner membrane lipoprotein; Protects the bacterial cell from host peptidases.
  
     0.613
yghU
Putative glutathione S-transferase; Similar to E. coli orf, hypothetical protein (AAC76025.1); Blastp hit to AAC76025.1 (304 aa), 91% identity in aa 17 - 303.
   
  
 0.613
ampD
N-acetyl-anhydromuramyl-L-alanine amidase; Involved in cell wall peptidoglycan recycling. Specifically cleaves the amide bond between the lactyl group of N-acetylmuramic acid and the alpha-amino group of the L-alanine in degradation products containing an anhydro N-acetylmuramyl moiety. Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.
      
 0.612
rtcB
Putative cytoplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76446.1); Blastp hit to AAC76446.1 (408 aa), 87% identity in aa 1 - 408.
  
     0.587
yijF
Putative periplasmic protein; Similar to E. coli orf, hypothetical protein (AAC76926.1); Blastp hit to AAC76926.1 (205 aa), 67% identity in aa 1 - 203.
  
     0.549
ybhC
Similar to E. coli putative pectinesterase (AAC73859.1); Blastp hit to AAC73859.1 (427 aa), 86% identity in aa 1 - 427.
  
     0.535
Your Current Organism:
Salmonella enterica Typhimurium
NCBI taxonomy Id: 99287
Other names: S. enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium LT2, Salmonella enterica subsp. enterica serovar Typhimurium str. LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2, Salmonella enterica subsp. enterica serovar Typhimurium strain LT2-LTL2, Salmonella typhimurium LT2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.