STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRO00153.1HAD superfamily hydrolase. (219 aa)    
Predicted Functional Partners:
KRN99631.1
CinA domain-containing protein; Belongs to the CinA family.
    
  0.931
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.924
guaB
Inosine 5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.923
KRN97950.1
Nucleoside triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
 
  0.916
KRN99344.1
Glycerol uptake facilitator related permease (major Intrinsic protein family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
   0.709
KRN98752.1
Glycerol uptake facilitator related permease (major Intrinsic protein family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
   0.709
KRN98126.1
Glycerol uptake facilitator protein; Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
   0.709
KRN95539.1
Glycerol uptake facilitator related permease (major Intrinsic protein family); Belongs to the MIP/aquaporin (TC 1.A.8) family.
   
   0.709
KRO00152.1
Acetylesterase.
   
 
 0.622
KRO00154.1
Hypothetical protein.
  
    0.589
Your Current Organism:
Lactobacillus kimchiensis
NCBI taxonomy Id: 993692
Other names: DSM 24716, JCM 17702, KACC 15533, L. kimchiensis, Lactobacillus kimchiensis Kim et al. 2013, Lactobacillus sp. L133, strain L133
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