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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CYP2E1Uncharacterized protein; Belongs to the cytochrome P450 family. (502 aa)    
Predicted Functional Partners:
EPHX1
Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family.
   
 0.957
CYP7A1
Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family.
  
 
0.955
LOC101119393
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.954
UGT2A3
UDP glucuronosyltransferase family 2 member A3; Belongs to the UDP-glycosyltransferase family.
   
 0.954
W5NXH7_SHEEP
Uncharacterized protein.
  
 0.952
W5PHP3_SHEEP
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.950
UGT2B7
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.949
W5PHZ3_SHEEP
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.948
UGT1A1
UDP-glucuronosyltransferase; Belongs to the UDP-glycosyltransferase family.
   
 0.946
CYP1A2
Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family.
  
 
0.943
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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