STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PIGSPhosphatidylinositol glycan anchor biosynthesis class S. (555 aa)    
Predicted Functional Partners:
PIGU
Phosphatidylinositol glycan anchor biosynthesis class U.
   
 0.999
PIGK
GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family.
   
 0.999
PIGT
Phosphatidylinositol glycan anchor biosynthesis class T.
   
 0.998
GPAA1
Glycosylphosphatidylinositol anchor attachment 1.
   
 0.998
PIGO
Phosphatidylinositol glycan anchor biosynthesis class O.
   
 0.960
PGAP1
GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins. GPI inositol deacylation may important for efficient transport of GPI- anchored proteins from the endoplasmic reticulum to the Golgi.
    
 0.931
PGLYRP2
Peptidoglycan recognition protein 2.
   
 0.923
PIGF
Phosphatidylinositol glycan anchor biosynthesis class F.
     
 0.922
ACP5
Tartrate-resistant acid phosphatase type 5.
   
  
 0.674
LIPA
Lipase; Belongs to the AB hydrolase superfamily. Lipase family.
      
 0.580
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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