STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PLEKHG3-2Uncharacterized protein. (163 aa)    
Predicted Functional Partners:
RHOU
Ras homolog family member U.
    
 0.590
SPATS1
Spermatogenesis associated serine rich 1.
      
 0.584
SYNGAP1
Synaptic Ras GTPase activating protein 1.
      
 0.583
BSN
Bassoon presynaptic cytomatrix protein.
      
 0.583
CYFIP2
Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family.
     
 0.570
MLLT11
MLLT11 transcription factor 7 cofactor.
      
 0.512
SGSM1
Small G protein signaling modulator 1.
      
 0.508
GABBR2
Gamma-aminobutyric acid type B receptor subunit 2.
      
 0.459
GRM1
Glutamate metabotropic receptor 1.
      
 0.457
NOS1AP
Nitric oxide synthase 1 adaptor protein.
      
 0.457
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.