STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NPF6_SHEEPLRRcap domain-containing protein. (247 aa)    
Predicted Functional Partners:
XPO1
Exportin 1.
   
 0.780
SET
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.691
H2AZ1
Histone H2A.Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post- translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for c [...]
   
 
 0.599
H2AZ2
Histone H2A; Belongs to the histone H2A family.
   
 
 0.599
W5P2I7_SHEEP
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.587
W5P9P7_SHEEP
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.587
W5PAK2_SHEEP
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.587
W5Q037_SHEEP
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.587
W5Q368_SHEEP
SARAH domain-containing protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.587
LOC101119456
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
   
 0.587
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.