FOSL1 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

FOSL1

FOS like 1, AP-1 transcription factor subunit. (286 aa)

Predicted Functional Partners:

JUN

0.894

MAPK13

0.794

JUNB

0.764

NFATC3

0.755

FOSL2

0.750

RUNX2

0.720

COL5A2

0.720

DVL3

0.716

MEPE

0.708

NCF2

0.701

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
COL5A2	DVL3	ENSOARP00000017663	ENSOARP00000022157	Collagen type V alpha 2 chain.	Dishevelled segment polarity protein 3.	0.758
COL5A2	FOSL1	ENSOARP00000017663	ENSOARP00000000050	Collagen type V alpha 2 chain.	FOS like 1, AP-1 transcription factor subunit.	0.720
COL5A2	MEPE	ENSOARP00000017663	ENSOARP00000003039	Collagen type V alpha 2 chain.	Matrix extracellular phosphoglycoprotein.	0.717
COL5A2	NFATC3	ENSOARP00000017663	ENSOARP00000003566	Collagen type V alpha 2 chain.	Nuclear factor of activated T cells 3.	0.693
COL5A2	RUNX2	ENSOARP00000017663	ENSOARP00000011107	Collagen type V alpha 2 chain.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.688
DVL3	COL5A2	ENSOARP00000022157	ENSOARP00000017663	Dishevelled segment polarity protein 3.	Collagen type V alpha 2 chain.	0.758
DVL3	FOSL1	ENSOARP00000022157	ENSOARP00000000050	Dishevelled segment polarity protein 3.	FOS like 1, AP-1 transcription factor subunit.	0.716
DVL3	MEPE	ENSOARP00000022157	ENSOARP00000003039	Dishevelled segment polarity protein 3.	Matrix extracellular phosphoglycoprotein.	0.710
DVL3	NFATC3	ENSOARP00000022157	ENSOARP00000003566	Dishevelled segment polarity protein 3.	Nuclear factor of activated T cells 3.	0.706
DVL3	RUNX2	ENSOARP00000022157	ENSOARP00000011107	Dishevelled segment polarity protein 3.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.613
FOSL1	COL5A2	ENSOARP00000000050	ENSOARP00000017663	FOS like 1, AP-1 transcription factor subunit.	Collagen type V alpha 2 chain.	0.720
FOSL1	DVL3	ENSOARP00000000050	ENSOARP00000022157	FOS like 1, AP-1 transcription factor subunit.	Dishevelled segment polarity protein 3.	0.716
FOSL1	FOSL2	ENSOARP00000000050	ENSOARP00000020928	FOS like 1, AP-1 transcription factor subunit.	FOS like 2, AP-1 transcription factor subunit.	0.750
FOSL1	JUN	ENSOARP00000000050	ENSOARP00000010722	FOS like 1, AP-1 transcription factor subunit.	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family.	0.894
FOSL1	JUNB	ENSOARP00000000050	ENSOARP00000011637	FOS like 1, AP-1 transcription factor subunit.	JunB proto-oncogene, AP-1 transcription factor subunit.	0.764
FOSL1	MAPK13	ENSOARP00000000050	ENSOARP00000013935	FOS like 1, AP-1 transcription factor subunit.	Mitogen-activated protein kinase.	0.794
FOSL1	MEPE	ENSOARP00000000050	ENSOARP00000003039	FOS like 1, AP-1 transcription factor subunit.	Matrix extracellular phosphoglycoprotein.	0.708
FOSL1	NCF2	ENSOARP00000000050	ENSOARP00000001785	FOS like 1, AP-1 transcription factor subunit.	Neutrophil cytosolic factor 2.	0.701
FOSL1	NFATC3	ENSOARP00000000050	ENSOARP00000003566	FOS like 1, AP-1 transcription factor subunit.	Nuclear factor of activated T cells 3.	0.755
FOSL1	RUNX2	ENSOARP00000000050	ENSOARP00000011107	FOS like 1, AP-1 transcription factor subunit.	Runt-related transcription factor; Forms the heterodimeric complex core-binding factor (CBF) with CBFB. RUNX members modulate the transcription of their target genes through recognizing the core consensus binding sequence 5'- TGTGGT-3', or very rarely, 5'-TGCGGT-3', within their regulatory regions via their runt domain, while CBFB is a non-DNA-binding regulatory subunit that allosterically enhances the sequence-specific DNA-binding capacity of RUNX.	0.720