STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHISA5Shisa family member 5. (197 aa)    
Predicted Functional Partners:
UNC79
Unc-79 homolog, NALCN channel complex subunit.
    
 0.689
IP6K2
Kinase; Belongs to the inositol phosphokinase (IPK) family.
      
 0.609
ITIH2
Inter-alpha-trypsin inhibitor heavy chain 2.
   
 0.606
PLPPR5
Phospholipid phosphatase related 5.
    
 0.606
PLPPR4
Phospholipid phosphatase related 4.
    
 0.596
LAMB2
Laminin subunit beta 2.
     
 0.557
USP19
Ubiquitin specific peptidase 19.
  
 
 0.557
CALHM2
Calcium homeostasis modulator family member 2.
      
 0.541
BAG4
BCL2 associated athanogene 4.
    
 
 0.537
RNF123
Ring finger protein 123.
    
 
 0.529
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.