STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PABPC1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (572 aa)    
Predicted Functional Partners:
PAIP1
Poly(A) binding protein interacting protein 1.
   
 0.996
EIF4E
Eukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family.
   
 0.984
UPF1
UPF1 RNA helicase and ATPase.
   
 0.971
EIF4B
Eukaryotic translation initiation factor 4B.
   
 0.967
EIF4G1
Eukaryotic translation initiation factor 4 gamma 1.
   
 0.956
EIF4H
Eukaryotic translation initiation factor 4H.
   
 0.936
SMG7
SMG7 nonsense mediated mRNA decay factor.
    
 0.934
SMG6
SMG6 nonsense mediated mRNA decay factor.
    
 0.928
HSPA8
Heat shock protein family A (Hsp70) member 8; Belongs to the heat shock protein 70 family.
   
 0.904
W5P773_SHEEP
Uncharacterized protein.
   
 0.904
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.