STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SHISA4Shisa family member 4. (162 aa)    
Predicted Functional Partners:
EDC4
Enhancer of mRNA decapping 4.
   
  
 0.834
ENDOV
Endonuclease V.
      
 0.823
PPP1R27
Protein phosphatase 1 regulatory subunit 27.
    
 
 0.823
PSKH1
Protein serine kinase H1; Belongs to the protein kinase superfamily.
      
 0.776
PPP1R3D
Protein phosphatase 1 regulatory subunit.
      
 0.758
TMEM9
Transmembrane protein 9.
      
 0.730
RAPSN
Receptor associated protein of the synapse.
      
 0.723
SH3D21
SH3 domain containing 21.
      
 0.689
LRRC40
Leucine rich repeat containing 40.
      
 0.683
BEND7
BEN domain containing 7.
      
 0.682
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.