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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NPK5_SHEEPA2M_recep domain-containing protein. (653 aa)    
Predicted Functional Partners:
W5NRI1_SHEEP
A2M_N_2 domain-containing protein.
 
     0.932
W5NXP6_SHEEP
Anaphylatoxin-like domain-containing protein.
 
     0.843
W5NRH2_SHEEP
Anaphylatoxin-like domain-containing protein.
 
     0.796
C2
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.686
C3AR1
Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family.
    
 0.650
CD55
Uncharacterized protein.
   
 0.649
CR2
Uncharacterized protein.
   
 0.626
CFI
Uncharacterized protein; Belongs to the peptidase S1 family.
   
 0.622
W5PWS0_SHEEP
Membrane cofactor protein; Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization.
    
 0.555
MASP2
Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family.
   
 0.539
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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