Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LMOD1Uncharacterized protein. (375 aa)    
Predicted Functional Partners:
LMOD2
Leiomodin 2.
   
 
0.910
LMOD3
Leiomodin 3.
   
 
0.910
MYH11
Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.
   
 
 0.819
CNN1
Calponin-1; Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
   
 
 0.786
RBPMS2
RNA binding protein, mRNA processing factor 2.
    
 0.785
MYL9
Myosin light chain 9.
   
 
 0.666
LYPD6B
LY6/PLAUR domain containing 6B.
      
 0.644
CCDC171
Coiled-coil domain containing 171.
      
 0.644
DENND3
DENN domain containing 3.
  
   
 0.640
TPM2
Uncharacterized protein; Belongs to the tropomyosin family.
   
 0.630
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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