STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PHC3Polyhomeotic homolog 3. (996 aa)    
Predicted Functional Partners:
CBX4
Chromobox 4.
    
 0.944
CBX2
Chromobox 2.
    
 0.940
CBX8
Chromobox 8.
    
 0.934
RNF2
Ring finger protein 2.
    
 0.925
RING1
Ring finger protein 1.
    
 0.925
BMI1
RING-type domain-containing protein.
   
 0.923
PCGF2
Polycomb group ring finger 2.
   
 0.923
SCMH1
Scm polycomb group protein homolog 1.
    
0.825
CBX7
Chromobox 7.
    
 0.769
PHC1
Polyhomeotic homolog 1.
    
0.754
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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