STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CCNKCyclin K; Belongs to the cyclin family. (431 aa)    
Predicted Functional Partners:
CDK12
Cyclin dependent kinase 12.
   
 0.999
CDK13
Cyclin dependent kinase 13.
   
 0.998
CDK9
Cyclin dependent kinase 9.
   
 0.976
CCNH
Cyclin H; Belongs to the cyclin family.
     
 0.927
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.829
ZNF276
Zinc finger protein 276.
    
 0.828
NELFE
Negative elongation factor complex member E.
    
 0.821
POLR2A
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.813
W5PMA1_SHEEP
Uncharacterized protein.
   
 0.812
W5PYZ4_SHEEP
Uncharacterized protein.
   
 0.812
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.