STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGDSTDP-glucose 4,6-dehydratase. (355 aa)    
Predicted Functional Partners:
GALT
Galactose-1-phosphate uridylyltransferase.
   
 
 0.959
UGDH
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
  
  
 0.941
GMPPB
GDP-mannose pyrophosphorylase B.
  
 
 0.852
COQ3
Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family.
  
 
 0.839
SLC35A1
Solute carrier family 35 member A1.
   
  
 0.837
EIF2B3
Eukaryotic translation initiation factor 2B subunit gamma.
  
 
 0.825
GMPPA
GDP-mannose pyrophosphorylase A.
  
 
 0.825
EIF2B5
Eukaryotic translation initiation factor 2B subunit epsilon.
  
 
 0.825
ALG11
ALG11 alpha-1,2-mannosyltransferase.
  
  
 0.813
GFOD2
Glucose-fructose oxidoreductase domain containing 2.
  
 
 0.772
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.