STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRWD3Bromodomain and WD repeat domain containing 3. (1800 aa)    
Predicted Functional Partners:
SH3BGRL3
Glutaredoxin domain-containing protein.
      
 0.825
TAOK1
TAO kinase 1.
   
 
 0.782
UBXN7
UBX domain-containing protein 7.
   
 0.781
ZNF711
Zinc finger protein 711.
   
 0.759
TBCK
TBC1 domain containing kinase.
      
 0.709
PIK3C2A
Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.
   
    0.672
W5NTY4_SHEEP
Uncharacterized protein.
   
 0.658
MYSM1
Myb like, SWIRM and MPN domains 1.
   
 0.643
APOOL
MICOS complex subunit; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
   
  
 0.628
RPS6KA6
Non-specific serine/threonine protein kinase.
   
  
 0.627
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.