STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NS75_SHEEPCyclic nucleotide-binding domain-containing protein. (1315 aa)    
Predicted Functional Partners:
CNGA1
Cyclic nucleotide gated channel subunit alpha 1.
  
0.999
CNGA4
Cyclic nucleotide gated channel subunit alpha 4.
  
0.978
CNGA2
Cyclic nucleotide gated channel subunit alpha 2.
  
0.977
CNGA3
Cyclic nucleotide-binding domain-containing protein.
   
0.833
GNAT1
G protein subunit alpha transducin 1.
   
 0.808
RHO
Rhodopsin; Photoreceptor required for image-forming vision at low light intensity. Required for photoreceptor cell viability after birth (By similarity). Light-induced isomerization of 11-cis to all-trans retinal triggers a conformational change that activates signaling via G- proteins. Subsequent receptor phosphorylation mediates displacement of the bound G-protein alpha subunit by the arrestin SAG and terminates signaling (By similarity).
   
 
 0.725
RPGR
Uncharacterized protein.
      
 0.722
CALML5
Calmodulin like 5.
   
 0.690
PDE6A
Phosphodiesterase.
   
 0.667
SMKR1
Small lysine rich protein 1.
      
 0.657
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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