Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WDR89WD repeat domain 89. (386 aa)    
Predicted Functional Partners:
NOL8
Nucleolar protein 8.
    
   0.806
SDAD1
Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.
   
    0.618
WDR43
WD repeat domain 43.
   
    0.597
NOC4L
Nucleolar complex associated 4 homolog.
   
    0.478
DHX8
DEAH-box helicase 8.
   
  
 0.475
UTP3
UTP3 small subunit processome component.
   
    0.472
DIMT1
rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
   
    0.463
RSL24D1
Ribosomal L24 domain containing 1.
   
    0.459
TTC17
Tetratricopeptide repeat domain 17.
      
 0.457
DDX56
DEAD-box helicase 56.
   
  
 0.441
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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