Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
EVA1AEva-1 homolog A, regulator of programmed cell death. (140 aa)    
Predicted Functional Partners:
AGBL5
ATP/GTP binding protein like 5.
      
 0.895
OSBPL6
Oxysterol-binding protein; Belongs to the OSBP family.
      
 0.809
ATF7
Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters.
      
 0.747
GLIPR1
GLI pathogenesis related 1; Belongs to the CRISP family.
      
 0.626
TPD52
Uncharacterized protein.
      
 0.612
GALNT13
Polypeptide N-acetylgalactosaminyltransferase.
      
 0.586
ANKRD50
Ankyrin repeat domain 50.
      
 0.565
AKAP12
A-kinase anchoring protein 12.
      
 0.515
ATG9A
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
      
 0.504
CFAP52
Cilia and flagella associated protein 52.
      
 0.503
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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