| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| A2M | ALB | ENSOARP00000001046 | ENSOARP00000014782 | Alpha-2-macroglobulin. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.760 |
| A2M | APOH | ENSOARP00000001046 | ENSOARP00000016806 | Alpha-2-macroglobulin. | Apolipoprotein H. | 0.701 |
| A2M | C3AR1 | ENSOARP00000001046 | ENSOARP00000021845 | Alpha-2-macroglobulin. | Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. | 0.703 |
| A2M | CP | ENSOARP00000001046 | ENSOARP00000005423 | Alpha-2-macroglobulin. | Ceruloplasmin; Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane (By similarity). | 0.747 |
| A2M | HSPA5 | ENSOARP00000001046 | ENSOARP00000013846 | Alpha-2-macroglobulin. | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | 0.690 |
| A2M | KLKB1 | ENSOARP00000001046 | ENSOARP00000008848 | Alpha-2-macroglobulin. | Kallikrein B1; Belongs to the peptidase S1 family. | 0.762 |
| A2M | LOC101102413 | ENSOARP00000001046 | ENSOARP00000004002 | Alpha-2-macroglobulin. | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.859 |
| A2M | PLG | ENSOARP00000001046 | ENSOARP00000005065 | Alpha-2-macroglobulin. | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.710 |
| A2M | SERPINA1 | ENSOARP00000001046 | ENSOARP00000015963 | Alpha-2-macroglobulin. | Alpha-1-antiproteinase; Inhibits human leukocyte elastase, pig pancreatic elastase and bovine trypsin on a 1:1 molar basis; Belongs to the serpin family. | 0.826 |
| A2M | TTR | ENSOARP00000001046 | ENSOARP00000006793 | Alpha-2-macroglobulin. | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.724 |
| ALB | A2M | ENSOARP00000014782 | ENSOARP00000001046 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-2-macroglobulin. | 0.760 |
| ALB | APOH | ENSOARP00000014782 | ENSOARP00000016806 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Apolipoprotein H. | 0.652 |
| ALB | CP | ENSOARP00000014782 | ENSOARP00000005423 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Ceruloplasmin; Ceruloplasmin is a blue, copper-binding (6-7 atoms per molecule) glycoprotein. It has ferroxidase activity oxidizing Fe(2+) to Fe(3+) without releasing radical oxygen species. It is involved in iron transport across the cell membrane (By similarity). | 0.828 |
| ALB | HSPA5 | ENSOARP00000014782 | ENSOARP00000013846 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. | 0.616 |
| ALB | LOC101102413 | ENSOARP00000014782 | ENSOARP00000004002 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Uncharacterized protein; Belongs to the peptidase S1 family. | 0.896 |
| ALB | PLG | ENSOARP00000014782 | ENSOARP00000005065 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] | 0.983 |
| ALB | SERPINA1 | ENSOARP00000014782 | ENSOARP00000015963 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Alpha-1-antiproteinase; Inhibits human leukocyte elastase, pig pancreatic elastase and bovine trypsin on a 1:1 molar basis; Belongs to the serpin family. | 0.913 |
| ALB | TTR | ENSOARP00000014782 | ENSOARP00000006793 | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain (By similarity). Belongs to the transthyretin family. | 0.875 |
| APOH | A2M | ENSOARP00000016806 | ENSOARP00000001046 | Apolipoprotein H. | Alpha-2-macroglobulin. | 0.701 |
| APOH | ALB | ENSOARP00000016806 | ENSOARP00000014782 | Apolipoprotein H. | Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...] | 0.652 |