STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AP5S1Adaptor related protein complex 5 subunit sigma 1. (203 aa)    
Predicted Functional Partners:
AP5B1
Adaptor related protein complex 5 subunit beta 1.
    
 0.920
ARFGAP2
ADP ribosylation factor GTPase activating protein 2.
      
 0.863
ZNF367
Zinc finger protein 367.
      
 0.862
ERMAP
Erythroblast membrane associated protein (Scianna blood group).
      
 0.845
ZBTB3
Zinc finger and BTB domain containing 3.
      
 0.835
SH3TC2
SH3 domain and tetratricopeptide repeats 2.
      
 0.830
RHCG
Ammonium_transp domain-containing protein; Belongs to the ammonium transporter (TC 2.A.49) family. Rh subfamily.
      
 0.771
KAT6B
Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.
      
 0.752
RND1
Rho family GTPase 1.
      
 0.728
ARL1
Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.
      
 0.714
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.