STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOX1NADPH oxidase 1. (593 aa)    
Predicted Functional Partners:
CYBA
Cytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide.
   
 0.999
NOXO1
NADPH oxidase organizer 1.
   
 0.993
NOXA1
NADPH oxidase activator 1.
   
 0.985
NCF1
Neutrophil cytosolic factor 1.
   
 0.965
NCF2
Neutrophil cytosolic factor 2.
   
 0.961
NOX4
NADPH oxidase 4.
  
0.863
NOX5
NADPH oxidase 5.
   
 
0.817
NOX3
NADPH oxidase 3.
  
  
0.806
RAC1
Uncharacterized protein.
   
 0.771
NCF4
Neutrophil cytosolic factor 4.
   
 0.713
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.