STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KRBA2KRAB-A domain containing 2. (429 aa)    
Predicted Functional Partners:
FANCM
FA complementation group M.
    
 0.657
MAP3K19
Mitogen-activated protein kinase kinase kinase 19.
   
 
 0.655
ADGRL3
Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family.
   
 
 0.589
KHDRBS2
KH RNA binding domain containing, signal transduction associated 2.
   
 
 0.571
C12orf50
Chromosome 12 open reading frame 50.
   
  
 0.543
PCDHAC2
Protocadherin alpha subfamily C, 2.
      
 0.536
C12orf29
Uncharacterized protein.
      
 0.522
THSD7B
Thrombospondin type 1 domain containing 7B.
      
 0.516
TMTC3
Transmembrane O-mannosyltransferase targeting cadherins 3.
    
 
 0.494
LOC105613870
Prostaglandin E2 omega-hydroxylase CYP4F21; A cytochrome P450 monooxygenase that catalyzes the omega- hydroxylation of prostaglandin E2. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (CPR; NADPH-ferrihemoprotein reductase).
   
 0.492
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.