TRPM5 protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Textmining

[Homology]

Score

TRPM5

Uncharacterized protein. (165 aa)

Predicted Functional Partners:

ASCL3

0.832

TAS1R3

0.817

CNGA2

0.773

DCLK1

0.757

TAS1R1

0.726

PLCB2

0.724

POU2F3

0.697

TRPV1

0.685

TRPV2

0.662

TRPC5

0.628

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ASCL3	CNGA2	ENSOARP00000018405	ENSOARP00000009206	Achaete-scute family bHLH transcription factor 3.	Cyclic nucleotide gated channel subunit alpha 2.	0.496
ASCL3	TRPM5	ENSOARP00000018405	ENSOARP00000001134	Achaete-scute family bHLH transcription factor 3.	Uncharacterized protein.	0.832
CNGA2	ASCL3	ENSOARP00000009206	ENSOARP00000018405	Cyclic nucleotide gated channel subunit alpha 2.	Achaete-scute family bHLH transcription factor 3.	0.496
CNGA2	TRPM5	ENSOARP00000009206	ENSOARP00000001134	Cyclic nucleotide gated channel subunit alpha 2.	Uncharacterized protein.	0.773
DCLK1	PLCB2	ENSOARP00000011263	ENSOARP00000021666	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.636
DCLK1	POU2F3	ENSOARP00000011263	ENSOARP00000018063	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	POU domain protein.	0.791
DCLK1	TAS1R3	ENSOARP00000011263	ENSOARP00000004590	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Taste 1 receptor member 3; Belongs to the G-protein coupled receptor 3 family.	0.641
DCLK1	TRPC5	ENSOARP00000011263	ENSOARP00000018853	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family.	0.400
DCLK1	TRPM5	ENSOARP00000011263	ENSOARP00000001134	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Uncharacterized protein.	0.757
PLCB2	DCLK1	ENSOARP00000021666	ENSOARP00000011263	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.636
PLCB2	POU2F3	ENSOARP00000021666	ENSOARP00000018063	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	POU domain protein.	0.620
PLCB2	TAS1R1	ENSOARP00000021666	ENSOARP00000012396	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Taste 1 receptor member 1.	0.790
PLCB2	TAS1R3	ENSOARP00000021666	ENSOARP00000004590	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Taste 1 receptor member 3; Belongs to the G-protein coupled receptor 3 family.	0.871
PLCB2	TRPM5	ENSOARP00000021666	ENSOARP00000001134	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	Uncharacterized protein.	0.724
POU2F3	DCLK1	ENSOARP00000018063	ENSOARP00000011263	POU domain protein.	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	0.791
POU2F3	PLCB2	ENSOARP00000018063	ENSOARP00000021666	POU domain protein.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.620
POU2F3	TRPM5	ENSOARP00000018063	ENSOARP00000001134	POU domain protein.	Uncharacterized protein.	0.697
TAS1R1	PLCB2	ENSOARP00000012396	ENSOARP00000021666	Taste 1 receptor member 1.	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.	0.790
TAS1R1	TAS1R3	ENSOARP00000012396	ENSOARP00000004590	Taste 1 receptor member 1.	Taste 1 receptor member 3; Belongs to the G-protein coupled receptor 3 family.	0.984
TAS1R1	TRPM5	ENSOARP00000012396	ENSOARP00000001134	Taste 1 receptor member 1.	Uncharacterized protein.	0.726