STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SBK1SH3 domain binding kinase 1. (376 aa)    
Predicted Functional Partners:
RASSF3
Ras association domain family member 3.
      
 0.706
RGS7BP
Regulator of G protein signaling 7 binding protein.
      
 0.706
TANC1
Tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1.
      
 0.704
RBM28
RNA binding motif protein 28.
      
 0.695
PPP2R5D
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
      
 0.685
RIOK3
Serine/threonine-protein kinase RIO3; Involved in regulation of type I interferon (IFN)-dependent immune response which plays a critical role in the innate immune response against DNA and RNA viruses.
      
 0.684
RASSF6
Ras association domain family member 6.
      
 0.666
PIP4K2B
Phosphatidylinositol-5-phosphate 4-kinase type 2 beta.
   
  
 0.639
TLCD4
TLC domain-containing protein.
   
  
 0.623
ADAM28
ADAM metallopeptidase domain 28.
   
  
 0.620
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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