STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ID1Inhibitor of DNA binding 1, HLH protein. (152 aa)    
Predicted Functional Partners:
TCF3
Transcription factor 3.
    
 
 0.973
ID3
BHLH domain-containing protein.
   
0.958
ETS2
ETS proto-oncogene 2, transcription factor.
     
 0.938
ID2
BHLH domain-containing protein.
  
  
0.921
THBS1
Thrombospondin 1.
    
 0.916
RAP1B
RAP1B, member of RAS oncogene family.
     
  0.900
RAP1A
RAP1A, member of RAS oncogene family.
     
  0.900
MYOD1
Myoblast determination protein 1; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation. Together with MYF5 and MYOG, co-occupies muscle-specific gene promoter core region during myogenesis. Induces fibroblasts to differentiate into myoblasts. Interacts with and is inhibited by the twist protein. This interaction probably involves the basic domains of both proteins (By similarity).
    
 
 0.687
TCF4
Transcription factor 4.
    
 
 0.641
TCF12
Transcription factor 12.
    
 
 0.641
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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