STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HERC6HECT domain-containing protein. (996 aa)    
Predicted Functional Partners:
ISG15
Uncharacterized protein.
   
 0.766
IFIT2
Interferon induced protein with tetratricopeptide repeats 2.
   
 
 0.683
UBE2L6
Ubiquitin conjugating enzyme E2 L6; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.681
RSAD2
Radical S-adenosyl methionine domain containing 2.
   
 
 0.643
VPS13D
Vacuolar protein sorting 13 homolog D.
      
 0.639
NUB1
Negative regulator of ubiquitin like proteins 1.
      
 0.602
RIMS4
Regulating synaptic membrane exocytosis 4.
      
 0.602
DET1
Uncharacterized protein.
     
 0.600
LOC101103965
USP domain-containing protein; Belongs to the peptidase C19 family.
   
 
 0.596
DENND5B
DENN domain containing 5B.
   
  
 0.595
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.