GRM8 protein (Ovis aries) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

GRM8

G_PROTEIN_RECEP_F3_4 domain-containing protein. (316 aa)

Predicted Functional Partners:

GRM7

0.944

W5PYC4_SHEEP

0.918

GNA12

0.916

GNA13

0.916

F2

0.906

AGT

0.905

CXCL8

0.900

W5NSR0_SHEEP

0.898

W5PCW8_SHEEP

0.845

RLN3

0.670

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGT	CXCL8	ENSOARP00000003247	ENSOARP00000015557	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family.	0.432
AGT	F2	ENSOARP00000003247	ENSOARP00000004316	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.605
AGT	GRM7	ENSOARP00000003247	ENSOARP00000008219	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	Glutamate metabotropic receptor 7.	0.905
AGT	GRM8	ENSOARP00000003247	ENSOARP00000001194	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.905
CXCL8	AGT	ENSOARP00000015557	ENSOARP00000003247	Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	0.432
CXCL8	GRM7	ENSOARP00000015557	ENSOARP00000008219	Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family.	Glutamate metabotropic receptor 7.	0.900
CXCL8	GRM8	ENSOARP00000015557	ENSOARP00000001194	Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.900
F2	AGT	ENSOARP00000004316	ENSOARP00000003247	Uncharacterized protein; Belongs to the peptidase S1 family.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	0.605
F2	GRM7	ENSOARP00000004316	ENSOARP00000008219	Uncharacterized protein; Belongs to the peptidase S1 family.	Glutamate metabotropic receptor 7.	0.906
F2	GRM8	ENSOARP00000004316	ENSOARP00000001194	Uncharacterized protein; Belongs to the peptidase S1 family.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.906
GNA12	GNA13	ENSOARP00000004746	ENSOARP00000016438	G protein subunit alpha 12.	G protein subunit alpha 13.	0.987
GNA12	GRM7	ENSOARP00000004746	ENSOARP00000008219	G protein subunit alpha 12.	Glutamate metabotropic receptor 7.	0.916
GNA12	GRM8	ENSOARP00000004746	ENSOARP00000001194	G protein subunit alpha 12.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.916
GNA13	GNA12	ENSOARP00000016438	ENSOARP00000004746	G protein subunit alpha 13.	G protein subunit alpha 12.	0.987
GNA13	GRM7	ENSOARP00000016438	ENSOARP00000008219	G protein subunit alpha 13.	Glutamate metabotropic receptor 7.	0.916
GNA13	GRM8	ENSOARP00000016438	ENSOARP00000001194	G protein subunit alpha 13.	G_PROTEIN_RECEP_F3_4 domain-containing protein.	0.916
GRM7	AGT	ENSOARP00000008219	ENSOARP00000003247	Glutamate metabotropic receptor 7.	Angiotensin 1-4; Essential component of the renin-angiotensin system (RAS), a potent regulator of blood pressure, body fluid and electrolyte homeostasis. [Angiotensin-3]: stimulates aldosterone release. Belongs to the serpin family.	0.905
GRM7	CXCL8	ENSOARP00000008219	ENSOARP00000015557	Glutamate metabotropic receptor 7.	Interleukin-8; IL-8 is a chemotactic factor that attracts neutrophils, basophils, and T-cells, but not monocytes. It is also involved in neutrophil activation. It is released from several cell types in response to an inflammatory stimulus; Belongs to the intercrine alpha (chemokine CxC) family.	0.900
GRM7	F2	ENSOARP00000008219	ENSOARP00000004316	Glutamate metabotropic receptor 7.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.906
GRM7	GNA12	ENSOARP00000008219	ENSOARP00000004746	Glutamate metabotropic receptor 7.	G protein subunit alpha 12.	0.916