NRIP1 protein (Ovis aries) - STRING interaction network

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Score

NRIP1

Nuclear receptor interacting protein 1. (1156 aa)

Predicted Functional Partners:

EP300

0.921

FOXA1

0.920

GATA3

0.913

ESR1

0.909

TLE3

0.864

RORA

0.842

RORC

0.821

TLE2

0.820

GMEB1

0.776

ESR2

0.746

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EP300	ESR1	ENSOARP00000019268	ENSOARP00000003565	E1A binding protein p300.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.956
EP300	ESR2	ENSOARP00000019268	ENSOARP00000022731	E1A binding protein p300.	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	0.797
EP300	FOXA1	ENSOARP00000019268	ENSOARP00000008788	E1A binding protein p300.	Forkhead box A1.	0.924
EP300	GATA3	ENSOARP00000019268	ENSOARP00000014958	E1A binding protein p300.	GATA binding protein 3.	0.937
EP300	NRIP1	ENSOARP00000019268	ENSOARP00000001205	E1A binding protein p300.	Nuclear receptor interacting protein 1.	0.921
EP300	RORA	ENSOARP00000019268	ENSOARP00000022374	E1A binding protein p300.	RAR related orphan receptor A.	0.625
EP300	RORC	ENSOARP00000019268	ENSOARP00000022633	E1A binding protein p300.	RAR related orphan receptor C.	0.499
EP300	TLE2	ENSOARP00000019268	ENSOARP00000014234	E1A binding protein p300.	TLE family member 2, transcriptional corepressor.	0.757
EP300	TLE3	ENSOARP00000019268	ENSOARP00000020073	E1A binding protein p300.	TLE family member 3, transcriptional corepressor.	0.816
ESR1	EP300	ENSOARP00000003565	ENSOARP00000019268	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	E1A binding protein p300.	0.956
ESR1	ESR2	ENSOARP00000003565	ENSOARP00000022731	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	0.997
ESR1	FOXA1	ENSOARP00000003565	ENSOARP00000008788	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Forkhead box A1.	0.932
ESR1	GATA3	ENSOARP00000003565	ENSOARP00000014958	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	GATA binding protein 3.	0.878
ESR1	NRIP1	ENSOARP00000003565	ENSOARP00000001205	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	Nuclear receptor interacting protein 1.	0.909
ESR1	TLE3	ENSOARP00000003565	ENSOARP00000020073	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	TLE family member 3, transcriptional corepressor.	0.609
ESR2	EP300	ENSOARP00000022731	ENSOARP00000019268	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	E1A binding protein p300.	0.797
ESR2	ESR1	ENSOARP00000022731	ENSOARP00000003565	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	Estrogen receptor; Nuclear hormone receptor. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Ligand-dependent nuclear transactivation involves either direct homodimer binding to a palindromic estrogen response element (ERE) sequence or association with other DNA-binding transcription factors, such as AP-1/c-Jun, c-Fos, ATF-2, Sp1 and Sp3, to mediate ERE- independent signaling. Ligand binding induces a conformational change allowing subsequent or combinatorial a [...]	0.997
ESR2	FOXA1	ENSOARP00000022731	ENSOARP00000008788	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	Forkhead box A1.	0.650
ESR2	GATA3	ENSOARP00000022731	ENSOARP00000014958	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	GATA binding protein 3.	0.527
ESR2	NRIP1	ENSOARP00000022731	ENSOARP00000001205	Estrogen receptor beta; Nuclear hormone receptor. Binds estrogens with an affinity similar to that of ESR1, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner; Belongs to the nuclear hormone receptor family. NR3 subfamily.	Nuclear receptor interacting protein 1.	0.746