STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FIZ1FLT3 interacting zinc finger 1. (329 aa)    
Predicted Functional Partners:
RSRC2
Arginine and serine rich coiled-coil 2.
    
 
 0.714
PPP6R1
Protein phosphatase 6 regulatory subunit 1.
    
 0.694
PRKCSH
Protein kinase C substrate 80K-H.
    
 
 0.653
RCOR3
REST corepressor 3.
    
 0.649
AKT1S1
AKT1 substrate 1.
   
 
 0.645
NRL
Neural retina leucine zipper.
    
 0.645
RDH13
Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
    
 
 0.638
ISOC2
Isochorismatase domain containing 2.
    
 
 0.635
DUXA
Double homeobox A.
   
 
 0.598
W5P6N3_SHEEP
Uncharacterized protein.
   
 
 0.598
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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