W5NSU1_SHEEP protein (Ovis aries) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

W5NSU1_SHEEP

Hyaluronidase. (553 aa)

Predicted Functional Partners:

CD44

0.934

GUSB

0.927

ARSB

0.909

ALB

0.892

ITSN2

0.833

HAS2

0.800

ITSN1

0.742

HAS1

0.738

PXDN

0.694

CD4

0.670

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ALB	CD4	ENSOARP00000014782	ENSOARP00000006749	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	0.974
ALB	CD44	ENSOARP00000014782	ENSOARP00000020204	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	CD44 molecule (Indian blood group).	0.813
ALB	GUSB	ENSOARP00000014782	ENSOARP00000001651	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Glyco_hydro_2_C domain-containing protein.	0.489
ALB	PXDN	ENSOARP00000014782	ENSOARP00000005666	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Peroxidasin.	0.983
ALB	W5NSU1_SHEEP	ENSOARP00000014782	ENSOARP00000001231	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Hyaluronidase.	0.892
ARSB	GUSB	ENSOARP00000018422	ENSOARP00000001651	Arylsulfatase B.	Glyco_hydro_2_C domain-containing protein.	0.488
ARSB	W5NSU1_SHEEP	ENSOARP00000018422	ENSOARP00000001231	Arylsulfatase B.	Hyaluronidase.	0.909
CD4	ALB	ENSOARP00000006749	ENSOARP00000014782	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.974
CD4	CD44	ENSOARP00000006749	ENSOARP00000020204	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	CD44 molecule (Indian blood group).	0.973
CD4	PXDN	ENSOARP00000006749	ENSOARP00000005666	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Peroxidasin.	0.785
CD4	W5NSU1_SHEEP	ENSOARP00000006749	ENSOARP00000001231	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	Hyaluronidase.	0.670
CD44	ALB	ENSOARP00000020204	ENSOARP00000014782	CD44 molecule (Indian blood group).	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.813
CD44	CD4	ENSOARP00000020204	ENSOARP00000006749	CD44 molecule (Indian blood group).	T-cell surface glycoprotein CD4; Accessory protein for MHC class-II antigen/T-cell receptor interaction. May regulate T-cell activation.	0.973
CD44	HAS1	ENSOARP00000020204	ENSOARP00000016021	CD44 molecule (Indian blood group).	Hyaluronan synthase 1.	0.541
CD44	HAS2	ENSOARP00000020204	ENSOARP00000011850	CD44 molecule (Indian blood group).	Hyaluronan synthase 2.	0.765
CD44	PXDN	ENSOARP00000020204	ENSOARP00000005666	CD44 molecule (Indian blood group).	Peroxidasin.	0.726
CD44	W5NSU1_SHEEP	ENSOARP00000020204	ENSOARP00000001231	CD44 molecule (Indian blood group).	Hyaluronidase.	0.934
GUSB	ALB	ENSOARP00000001651	ENSOARP00000014782	Glyco_hydro_2_C domain-containing protein.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.489
GUSB	ARSB	ENSOARP00000001651	ENSOARP00000018422	Glyco_hydro_2_C domain-containing protein.	Arylsulfatase B.	0.488
GUSB	W5NSU1_SHEEP	ENSOARP00000001651	ENSOARP00000001231	Glyco_hydro_2_C domain-containing protein.	Hyaluronidase.	0.927