STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NSU2_SHEEPUncharacterized protein. (366 aa)    
Predicted Functional Partners:
PDE6D
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
    
 0.871
TBCD
Tubulin folding cofactor D.
    
 0.847
W5Q5W8_SHEEP
ARL2_Bind_BART domain-containing protein.
   
 0.756
ARL2BP
ARL2_Bind_BART domain-containing protein.
   
 0.756
UNC119
Unc-119 lipid binding chaperone.
    
 
 0.716
ARL16
ADP ribosylation factor like GTPase 16.
      
 0.707
MYBPC1
Myosin binding protein C, slow type.
      
 0.482
TMEM67
Transmembrane protein 67.
      
 0.478
TBCB
Tubulin folding cofactor B.
   
  
 0.438
TBCE
Uncharacterized protein.
    
 
 0.419
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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