STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ATPAF2ATP synthase mitochondrial F1 complex assembly factor 2. (289 aa)    
Predicted Functional Partners:
TMEM70
Transmembrane protein 70.
   
  
 0.772
ATP23
Mitochondrial inner membrane protease ATP23; Belongs to the peptidase M76 family.
   
 
 0.715
ATP6
ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...]
      
 0.661
W5NX73_SHEEP
Uncharacterized protein.
   
 
 0.658
W5PCA9_SHEEP
Uncharacterized protein.
   
 
 0.658
GID4
GID complex subunit 4 homolog.
      
 0.654
UQCR10
Ubiquinol-cytochrome c reductase, complex III subunit X.
   
  
 0.642
ATP5F1B
ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane.
    
 
 0.617
NDUFS4
NADH:ubiquinone oxidoreductase subunit S4.
  
   
 0.586
CEP72
Centrosomal protein 72.
      
 0.571
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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