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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TAS2R3Taste receptor type 2. (316 aa)    
Predicted Functional Partners:
TAS2R4
Taste receptor type 2.
  
 
0.763
GNAT3
G protein subunit alpha transducin 3.
     
 0.663
LOC106990261
Olfactory receptor.
     
 0.584
TAS1R3
Taste 1 receptor member 3; Belongs to the G-protein coupled receptor 3 family.
     
 0.564
TAS1R1
Taste 1 receptor member 1.
     
 0.548
CASR
Calcium sensing receptor.
     
 0.544
W5P222_SHEEP
Olfactory receptor.
     
 0.541
PRKD1
Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
      
 0.537
GRM6
Glutamate metabotropic receptor 6.
     
 0.534
GRM2
Glutamate metabotropic receptor 2.
     
 0.534
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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