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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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Score
PRKAR1BProtein kinase cAMP-dependent type I regulatory subunit beta. (381 aa)    
Predicted Functional Partners:
PRKACA
cAMP-dependent protein kinase catalytic subunit alpha; Phosphorylates a large number of substrates in the cytoplasm and the nucleus. Regulates the abundance of compartmentalized pools of its regulatory subunits through phosphorylation of PJA2 which binds and ubiquitinates these subunits, leading to their subsequent proteolysis. Phosphorylates CDC25B, ABL1, NFKB1, CLDN3, PSMC5/RPT6, PJA2, RYR2, RORA and VASP. RORA is activated by phosphorylation. Required for glucose- mediated adipogenic differentiation increase and osteogenic differentiation inhibition from osteoblasts. Involved in the [...]
   
 0.875
PRKACB
Protein kinase cAMP-activated catalytic subunit beta; Belongs to the protein kinase superfamily.
   
 0.875
PRKX
Uncharacterized protein.
   
 0.850
C5orf30
Chromosome 5 open reading frame 30.
      
 0.768
PRKAR2A
Protein kinase cAMP-dependent type II regulatory subunit alpha.
  
  
0.717
PRKAR2B
Protein kinase cAMP-dependent type II regulatory subunit beta.
  
  
0.712
AK8
Adenylate kinase 8; Belongs to the adenylate kinase family.
   
 
 0.708
AKAP1
A-kinase anchoring protein 1.
    
 0.708
AKAP10
A-kinase anchoring protein 10.
   
 0.689
W5PRK3_SHEEP
Cyclic nucleotide-binding domain-containing protein.
  
  
0.645
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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