Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CHCHD4Coiled-coil-helix-coiled-coil-helix domain containing 4. (140 aa)    
Predicted Functional Partners:
GFER
Sulfhydryl oxidase.
    
 0.968
TIMM10
Translocase of inner mitochondrial membrane 10.
   
 0.927
AIFM1
Apoptosis inducing factor mitochondria associated 1.
    
 
 0.906
NDUFS5
NADH:ubiquinone oxidoreductase subunit S5.
    
 
 0.901
TIMM9
Translocase of inner mitochondrial membrane 9.
   
 0.883
LOC101107153
Uncharacterized protein.
   
 0.868
NFE2L1
Nuclear factor, erythroid 2 like 1.
      
 0.821
W5NV07_SHEEP
Uncharacterized protein.
   
 0.819
LONP1
Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial promoters and RNA in a single-stranded, site-specific, and strand- specific manner. May regulate mi [...]
   
  
 0.760
W5NSC6_SHEEP
zf-Tim10_DDP domain-containing protein; Belongs to the small Tim family.
   
 0.746
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
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