W5NSZ9_SHEEP protein (Ovis aries) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

W5NSZ9_SHEEP

Protein kinase domain-containing protein. (253 aa)

Predicted Functional Partners:

DCUN1D5

0.687

TEDDM1

0.623

STKLD1

0.585

LIMS1

0.570

NME8

0.565

METTL21C

0.538

MSMO1

0.526

PROCA1

0.522

TTLL9

0.513

PIK3C2A

0.483

Your Current Organism:

Ovis aries

NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DCUN1D5	LIMS1	ENSOARP00000004880	ENSOARP00000000446	DCN1-like protein.	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.	0.570
DCUN1D5	METTL21C	ENSOARP00000004880	ENSOARP00000005491	DCN1-like protein.	Methyltransferase like 21C.	0.704
DCUN1D5	W5NSZ9_SHEEP	ENSOARP00000004880	ENSOARP00000001289	DCN1-like protein.	Protein kinase domain-containing protein.	0.687
LIMS1	DCUN1D5	ENSOARP00000000446	ENSOARP00000004880	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.	DCN1-like protein.	0.570
LIMS1	METTL21C	ENSOARP00000000446	ENSOARP00000005491	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.	Methyltransferase like 21C.	0.404
LIMS1	W5NSZ9_SHEEP	ENSOARP00000000446	ENSOARP00000001289	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.	Protein kinase domain-containing protein.	0.570
METTL21C	DCUN1D5	ENSOARP00000005491	ENSOARP00000004880	Methyltransferase like 21C.	DCN1-like protein.	0.704
METTL21C	LIMS1	ENSOARP00000005491	ENSOARP00000000446	Methyltransferase like 21C.	LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors.	0.404
METTL21C	W5NSZ9_SHEEP	ENSOARP00000005491	ENSOARP00000001289	Methyltransferase like 21C.	Protein kinase domain-containing protein.	0.538
MSMO1	W5NSZ9_SHEEP	ENSOARP00000017317	ENSOARP00000001289	Methylsterol monooxygenase 1; Belongs to the sterol desaturase family.	Protein kinase domain-containing protein.	0.526
NME8	STKLD1	ENSOARP00000008843	ENSOARP00000003697	NME/NM23 family member 8.	Serine/threonine kinase like domain containing 1.	0.527
NME8	W5NSZ9_SHEEP	ENSOARP00000008843	ENSOARP00000001289	NME/NM23 family member 8.	Protein kinase domain-containing protein.	0.565
PIK3C2A	TEDDM1	ENSOARP00000004688	ENSOARP00000005655	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Transmembrane epididymal protein 1.	0.539
PIK3C2A	W5NSZ9_SHEEP	ENSOARP00000004688	ENSOARP00000001289	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	Protein kinase domain-containing protein.	0.483
PROCA1	W5NSZ9_SHEEP	ENSOARP00000003549	ENSOARP00000001289	Protein interacting with cyclin A1.	Protein kinase domain-containing protein.	0.522
STKLD1	NME8	ENSOARP00000003697	ENSOARP00000008843	Serine/threonine kinase like domain containing 1.	NME/NM23 family member 8.	0.527
STKLD1	W5NSZ9_SHEEP	ENSOARP00000003697	ENSOARP00000001289	Serine/threonine kinase like domain containing 1.	Protein kinase domain-containing protein.	0.585
TEDDM1	PIK3C2A	ENSOARP00000005655	ENSOARP00000004688	Transmembrane epididymal protein 1.	Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family.	0.539
TEDDM1	W5NSZ9_SHEEP	ENSOARP00000005655	ENSOARP00000001289	Transmembrane epididymal protein 1.	Protein kinase domain-containing protein.	0.623
TTLL9	W5NSZ9_SHEEP	ENSOARP00000002259	ENSOARP00000001289	Tubulin tyrosine ligase like 9.	Protein kinase domain-containing protein.	0.513