STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
W5NT20_SHEEPSodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (552 aa)    
Predicted Functional Partners:
SLC9A3R1
Na(+)/H(+) exchange regulatory cofactor NHE-RF; Scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression.
   
 
 0.754
CHP1
Calcineurin like EF-hand protein 1.
   
 0.727
WIPF2
WAS/WASL interacting protein family member 2.
      
 0.692
W5Q4Z4_SHEEP
PDZ domain-containing protein.
   
 
 0.639
UBASH3B
Ubiquitin associated and SH3 domain containing B.
   
  
 0.627
ZNF330
Zinc finger protein 330.
      
 0.623
CHP2
Calcineurin like EF-hand protein 2.
   
 0.618
SLC12A4
Uncharacterized protein.
    
 
 0.600
SLC4A2
Anion exchange protein.
    
 
 0.596
SLC28A1
Sodium/nucleoside cotransporter; Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.
      
 0.594
Your Current Organism:
Ovis aries
NCBI taxonomy Id: 9940
Other names: O. aries, Ovis ammon aries, Ovis orientalis aries, Ovis ovis, domestic sheep, lambs, sheep, wild sheep
Server load: low (12%) [HD]